Antitumor

Miltefosine

Miltefosine is primarily used as an antileishmanial drug with demonstrated activity against other parasites, cancer cells, and pathogenic bacteria and fungi.Mechanism of ActionSeveral potential antileishmanial mechanisms of action have been proposed...

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Indole-3-carbinol

Indole-3-carbinol is an indole found in many cruciferous vegetables with a variety of bioactivity including anticancer, antibacterial and antifungal effects. Researchers have found that in some cases indole-3-carbinol has inhibited angiogenesis, induced...

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Lactoferricin B, fragment 4-14 trifluoroacetate salt

Lactoferricin B is a broad-spectrum antimicrobial peptide (AMP) that is generated by the enzymatic digestion of lactoferrin. Lactoferricin B is derived from bovine lactoferrin. Lactoferricin B has activity against gram-positive and gram-negative...

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Posaconazole

Posaconazole is a synthetic, broad-spectrum, second generation triazole with antifungal activity. It has potent in vitro and in vivo trypanocidal activity. It was discovered by Schering-Plough and it is a structural analog of itraconazole.  It has...

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Flubendazole

Flubendazole is a pharmalogical common antihelmintic used to treat internal parasites. Researchers have been exploring its ability to inhibit tubulin for use in cancer treatment following successful demonstrations of cytotoxicity.Mechanism of...

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Isoxanthohumol

Isoxanthohumol is one of many bioactive prenylflavonoids that can be isolated from the hops plant, or Humulus lupulus L. While the primary research interest is in its apparent chemotherapeutic prevention activity, isoxanthohumol has also shown notable...

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Magainin II

Magainin II is an antimicrobial peptide originally isolated from Xenopus laevis, with excellent antibiotic activity across a broad-spectrum. It has also demonstrated antifungal activity in vitro and anticancer activity in vitro and in a mouse model...

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Icariin

Icariin is a flavonol glycoside that can be found in traditionally medicinal herb Herb Epimedii. Like many  other flavonoids, it exhibits pharmalogically promising bioactivities. Icariin in particular has shown antioxidant, anti-inflammatory,...

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PGLa

PGLa is an antimicrobial peptide (AMP) composed of 21 amino acids which form an α-helical secondary structure. Like many AMPs PGLa exerts a wide variety of antimicrobial activity including activity against fungi, viruses, gram-negative and...

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Pentostatin

Pentostatin is a potent antitumor antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used therapeutically as an antitumor agent.Pentostatin is soluble in ethanol, methanol, DMF or DMSO...

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LL-37 (human) Trifluoroacetate Salt

LL-37 (human) Trifluoroacetate Salt (LL-37) is a naturally-occuring antimicrobial peptide that is part of the innate host immune system. It is associated with the epidermis and protects the host from bacterial infection. LL-37 has also demonstrated a...

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Lasalocid Sodium

Lasalocid Sodium is the salt form of Lasalocid, a carboxylic polyether ionophore. The compound has anticancer properties and antibacterial activity. Lasalocid is isolated from Streptomyces lasaliensis, first reported in 1951. It is also known as a...

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