Virginiamycin S1 is a cyclic hexadepsipeptide. Together with Virginiamycin M1 as a mixture, it works synergistically against Gram-positive bacteria with bateriostatic properties. Commercial...
Tetromycin B is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin B has pronounced activity against antibiotic...
Teicoplanin A2-3 is a major analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad-spectrum antibiotic activity against Gram-positive...
The fungal metabolite, thielavin A, and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a...
Teicoplanin A2-4 is an analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram-positive bacteria,...
Teicoplanin A2-5 is the most non-polar analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad-spectrum antibiotic activity against...
Thielavin B is a fungal metabolite closely related to thielavin A but reported to have a slightly different biochemical profile. Thielavin B is a potent inhibitor of phospholipase C, and inhibits...
The tetronic acid, chlorothricin, is an unusual macrocyclic antibiotic from a Streptomyces sp., related to kijanimicin, saccharocarcins, tetrocarcins and versipelostatin. Chlorothricin inhibits...
Tiamulin is a semi-synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity and an...
Teicoplanin A3-1 is a minor polar analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad-spectrum antibiotic activity against...
Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was not solved until 1968. Telomycin possesses potent and highly selective activity against Gram positive...
TPU-0037A (30-Demethyllydicamycin), a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037A is also closely related to BN 4515N which was isolated from...
