Antibacterials

Alphitonin

Alphitonin is a flavonoid-related metabolite related to quercetin isolated from the heartwood of the Australian red ash, Alphitonia excela in 1922. Alphitonin's structure was reported by Birch and Ritchie in 1960. Alphitonin is thermally and enzymically...

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Asperuloside

Asperuloside is an iridoid monoterpenoid glycoside derived from the Rubiaceae family of flowering plants first reported in 1893.  More recently, Asperuloside was reported to have been efficiently isolated from Coprosma quadrifida via rapid...

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Acetoxypolygodial

Acetoxypolygodial is a drimane sesquiterpene isolated from the leaves and stems of Tasmannia lanceolata and bark of Canella winterana, and present in other plant species. Acetoxypolygodial is antifungal and weakly cytotoxic, and is potently active...

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Aszonapyrone A

Aszonapyrone A is a polycyclic meroditerpene, initially isolated from Aspergillus zonatus by Isogai and collaborators at Tottori University, Japan and subsequently from other Aspergillus species. Aszonapyrone A is active against multidrug-resistant...

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A 26771B

A 26771B is a 16-membered macrocyclic lactone isolated from Penicillium turbatum patented and then published by Eli Lilly and Co. in 1975. A 26771B is closely related to the berkeleylactones, recently reported as antibiotics derived from a cofermentation...

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Berkeleylactone E

Berkleylactone E is a major analog of a family of recently described macrolide antibiotics, isolated from a mixed fermentation of two Penicillium species. Berkleylactone E is active against Gram-positive bacteria, Candida albicans and Candida glabrata,...

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Berkeleylactone F

Berkleylactone F is a major analog of a family of recently described macrolide antibiotics, isolated from a mixed fermentation of two Penicillium species. Berkleylactone F is active against Gram-positive bacteria, Candida albicans and Candida glabrata,...

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Collinin

Collinin is a terpenylated coumarin isolated from Flindersia maculosa and other species by Ritchie and colleagues at Sydney University, Australia in 1954. Collinin possesses broad spectrum activity as an inhibitor of inflammation, collagenase and the...

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Chevalone E

Chevalone E is a minor analogue of the meroterpenoid chevalone family, isolated from Aspergillus similanensis by researchers in Portugal. Chevalone E is closely related to the aszonapyrones and sartorypyrones. Chevalone E is synergistic when used with...

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Evoxanthine

Evoxanthine is a furoacridone alkaloid isolated from Evodia xanthoxyloides by Hughes and Neill, University of Sydney, Australia in 1949. Evoxanthine is active against Gram-positive and Gram-negative bacteria, including E. coli, B. subtilis and M. luteus,...

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Galbinic Acid

Galbinic Acid (α-acetylsalazinic acid) is a depsidone isolated from the lichen, Usnea undulata. The structure of galbinic acid was elucidated by Elix, Australian National University in 1975. Galbinic Acid is moderately active against Gram-positive...

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Leoidin

Leoidin is a metabolite of the lichen, Lecanora gangleoides, first published in 1986 and recently reported as an inhibitor ofprotein synthesis in Pseudomonas aeruginosa. Leoidin is bacteriostatic, targeting PheRS. Leoidin is a weak inhibitor of human...

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