Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal...
Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. Despite the common mode of action, there is evidence that individual members display diverse selectivity...
Cytochalasin H is one of a family of potent mycotoxins produced by a range of fungi. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumor activity.Cytochalasin H...
Borrelidin is an unusual nitrile-containing metabolite isolated from Streptomyces. Borrelidin is an important lead for antimalarial discovery, displaying activity against drug-resistant Plasmodia...
Doramectin aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of doramectin. Doramectin aglycone is an inhibitor of nematode larval development, but is devoid of...
Epi-Doramectin is a base-catalysed intermediate in the decomposition of doramectin. epi-Doramectin is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the...
Delta-2-Doramectin is an irreversible base degradation product of doramectin found in animals treated with doramectin and in the environment. ?2-Doramectin is formed by rearrangement of the naturally...
Drimentine A belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibiotic, antifungal and anthelmintic activity. Unlike Drimentine B and...
Drimentine B belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibiotic, antifungal and anthelmintic activity.Drimentine B is soluble in...
Drimentine C belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibiotic, antifungal and anthelmintic activity.Drimentine C is soluble in...
Dihydrospinosyn A aglycone is an acid degradation product produced by hydrolysis of both saccharide groups of 3'-ethoxy-5,6-dihydrospinosyn J, the major component of the commercial insecticide,...
Concanamycin B is a macrocyclic lactone originally isolated from Streptomyces diastatochromogenes in 1982 as a potent inhibitor of the proliferation of mouse splenic lymphocytes stimulated by...
