Pyrocoll is a small secondary metabolite formed by the dimerisation of pyrrole-2-carboxylic acid and produced by many Streptomyces species. Pyrocoll is an important dereplication standard in...
Nystatin is a fungicidal and fungistatic polyene antifungal and growth promoter, first reported in 1950. It is a complex of three components: A1, A2 and A3. Nystatin functions by accumulating...
Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin...
Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced...
Cytochalasin C is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic...
Aphidicolin is a tetracyclic diterpene antibiotic isolated from fungi, notably Cephalosporium, Nigrospora, Harziella and Phoma. Aphidicolin has antibiotic, antiviral and antimitotic properties,...
Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death...
Lincomycin is a lincosamide first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial contains a rare amino acid (4-propyl-N-methylprolin) coupled to...
Narasin (4-methylsalinomycin) is a carboxylic polyether antibiotic isolated from Streptomyces aureofaciens in 1978. Although Narasin is a derivative of Salinomycin, the metabolites are produced by...
Bassianolide is a cyclooctadepsipeptide insecticide isolated from the entomopathogenic fungi, Beauveria bassiana and Verticillium lecanii, first reported by University of Tokyo researchers in 1978. ...
Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidal antibiotic, also exhibiting antifungal and antiviral...
epi-Avermectin B1a is a base-catalysed intermediate in the decomposition of Avermectin B1a. Epi-Avermectin B1a is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to...
