Immunosuppressants

Brefeldin A ReadyMade™ Solution

Brefeldin A ReadyMadeTM Solution (BFA) is provided as a sterile-filtered solution of Brefeldin A formulated in DMSO at a concentration of 10 mg/ml.  It has been filter-sterilized using a 0.22 μm filter.  Brefeldin A is a fungal metabolite...

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Mycophenolic Acid ReadyMade™ Solution

Mycophenolic Acid ReadyMade™ Solution is provided as a sterile-filtered solution formulated in β-cyclodextrin solution at a concentration of 12.5 mg/ml for enhanced solubility. Mycophenolic Acid is a natural active metabolite of Mycophenolate...

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Neosartoricin B

Neosartoricin B was produced biosynthetically in 2013 by Tang and colleagues from UCLA USA by selecting the gene cluster for neosartoricin that is homologous to a conserved cluster among dermatophytes of the Trichophyton and Arthroderma genera. When...

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Neosartoricin

Neosartoricin is a carbotricyclic metabolite produced by Aspergillus fumigatus and Neosartorya fischeri following activation of their polycyclic polyketide prenyltransferase (pcPTase)-containing silent clusters, reported by Tang and...

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Ethyl Mycophenolate

Ethyl mycophenolate is the ethyl ester of mycophenolic acid produced by Penicillium brevicompactum but devoid of the antifungal activity of mycophenolic acid. There are few reports of the biological activity of ethyl mycophenolate, however its analogue...

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Aminopterin

Aminopterin is a 4-amino derivative of folic acid and a folic acid antagonist. It is a synthetic derivative of pterin. It has both mmunosuppressive properties and anti-cancer properties and can be used for apoptosis research. The compound was discovered...

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Sulfasalazine

Sulfasalazine is a synthetic salicylic acid derivative and sulfonamide which can act as an antirhematic and gastrointestinal agent. It is formulated as a prodrug, and is metabolized into active metabolites sulfapyridine and mesalazine (5-aminosalicylic...

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Methotrexate Sodium

Methotrexate Sodium is a selective agent for dihydrofolate reductase (DHFR)- transfected cells and a nucleic acid synthesis inhibitor in protein expression systems. It is commonly used as an ancillary material in upstream biomanufacturing applications...

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Lactoferricin B, fragment 4-14 trifluoroacetate salt

Lactoferricin B is a broad-spectrum antimicrobial peptide (AMP) that is generated by the enzymatic digestion of lactoferrin. Lactoferricin B is derived from bovine lactoferrin. Lactoferricin B has activity against gram-positive and gram-negative...

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LL-37 (human) Trifluoroacetate Salt

LL-37 (human) Trifluoroacetate Salt (LL-37) is a naturally-occuring antimicrobial peptide that is part of the innate host immune system. It is associated with the epidermis and protects the host from bacterial infection. LL-37 has also demonstrated a...

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Melittin

Melittin is the principal toxic component of honey bee venom from Apis mellifera, making up 50% of its dry weight. It is a 26 residue long antimicrobial peptide has an α-helical conformation, and associates strongly with membranes. It has demonstrated...

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Matrine

Matrine is a natural alkaloid extracted from the Chinese herb Sophora flavescens.  Matrine has demonstrated antiviral and anti-inflammatory bioactivity with relatively low toxicity.  It has been used for cancer resarch and has been shown to...

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