Antimicrobials

A 54556B

A 54556B is an unusual depsipeptide isolated from Streptomyces hawaiiensis as antibiotics by researchers at Eli Lilly in 1985, featuring a trienone side chain. A 54556B is a potent antibacterial against Gram positive and Gram negative bacteria including...

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Amphomycin

Amphomycin is a lipopeptide antibiotic produced by Streptomycetes and Actinoplanes, initially isolated by researchers at Bristol-Myers in 1953 from Streptomyces canus.  Amphomycin was marketed as a complex of closely related analogs in the 1950s and...

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A 83016F

A 83016F is an unusual polyene originally isolated from an unidentified actinomycete and reported in 1992. Structurally, A 83016F is related to the phenelfamycins. A 83016F exhibits activity against Gram positive bacteria.A 83016F is soluble...

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Colistin Sulfate, EP

Colistin sulfate, EP (syn: polymyxin E) is a cationic, cyclic polypeptide antibiotic belonging to the polymyxin family. It is a natural product discovered in 1949 that is nonribosomally synthesized by Bacillus polymyxa subspecies colistinus...

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Vancomycin Hydrochloride, CulturePure®

Vancomycin Hydrochloride, CulturePure® (Vancomycin HCl) is a glycopeptide antibiotic derived from Streptomyces orientalis that was discovered in 1953 from a soil sample found in Borneo. It is effective against Gram-positive bacteria such as...

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Cefotaxime Sodium, CulturePure®

Cefotaxime Sodium, CulturePure® is a broad-spectrum, third-generation, β-lactamase-resistant cephalosporin antibiotic. The product is ≥99.0% pure and is uniquely designed for cell/plant culture applications. It has been carefully tested to...

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Tunicamycin

The tunicamycins are a family of lipophilic nucleosides with fatty acids conjugated to an aminoglycoside group. The complex comprises the analogues, tunicamycins I to X. This composition is typical of other products less precisely described as...

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Plumieride

Plumieride is a widely bioactive compound able to be isolated from several plants. Plumieride specifically is cytotoxic, and essential oils and ethanol extracts of plants containing Plumieride have been found to act as a diuretic, antibacterial,...

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Bicyclomycin

Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites.Bicyclomycin is soluble in ethanol, methanol, DMF and DMSO...

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Azidamfenicol

Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in 1959. Azidamfenicol is a broad spectrum antibiotic with...

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Bicyclomycin benzoate

Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972, with activity against Gram negative bacteria. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites, and in an effort to...

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Bromamphenicol

Bromamphenicol is a semi-synthetic chloramphenicol analogue first reported in 1950, in which the dichloroacetamide is replaced with dibromoacetamide. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol...

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