Antibacterials

Oosporein

Oosporein is a purple-red pigment published as a metabolite of Acremonium sp. in 1959. Oosporein has antibacterial, antiviral and antifungal activity. Oosporein is produced by the entomopathogenic fungus Beauveria bassiana after host death, acting to...

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Nikkomycin Z

Nikkomycin Z is a natural product, a nucleoside-type antibiotic isolated from Steptomyces tendae in the mid-1970s. Nikkomycin Z has potent narrow-spectrum activity against some fungi, including Rhizopus cirdinans, Colletrotrichum trifolii and Botrytis...

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Neosartoricin B

Neosartoricin B was produced biosynthetically in 2013 by Tang and colleagues from UCLA USA by selecting the gene cluster for neosartoricin that is homologous to a conserved cluster among dermatophytes of the Trichophyton and Arthroderma genera. When...

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Neosartoricin

Neosartoricin is a carbotricyclic metabolite produced by Aspergillus fumigatus and Neosartorya fischeri following activation of their polycyclic polyketide prenyltransferase (pcPTase)-containing silent clusters, reported by Tang and...

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Nanangenine H

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine H is an acylated drimane which is a putative biosynthetic intermediate of the higher nanagenines...

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Nanangenine G

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine G is an acylated drimane which is a putative biosynthetic intermediate of the higher...

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Nanangenine F

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine F is an acylated drimane and putative biosynthetic intermediate of the higher nanangenines...

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Nanangenine D

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine D is a drimane lactone bearing a C8 acyl side chain. Nanangenine D has potent activity against B...

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Nanangenine C

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine D is a drimane lactone bearing a C6 acyl side chain. Nanangenine D has potent activity against B...

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Nanangenine B

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine B is a drimane lactone bearing a C6 acyl side chain. Nanangenine C has weak activity against B...

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Monascinol

Monascinol is a yellow-orange pigment isolated from the fungus Monascus purpureus used to produce red yeast ric . Monascinol increases the efficacy of irradiation in PC-3 prostate cancer cells, enhancing DNA damage and endoplasmic reticulum stress...

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Nanangenine A

The nanangenines are newly discovered drimane sesquiterpenoid metabolites from a hitherto undescribed Australian fungus, Aspergillus nanangensis. Nanangenine A is a trihydroxylated drimane lactone which was inactive in assays for antibiotic, cytotoxic,...

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