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Pluviatolide is a butyrolactone lignan first isolated from the Australian native plant, Zanthoxylum pluviatile, by Taylor and Ritchie in 1970. More recently, Pluviatolide and the related hinokinin were reported as metabolites of the vine, Aristolochia...
Polygodial is a sesquiterpene dialdehyde first isolated from Persicaria hydropiper (syn. Polygonum hydropiper) by Loder atCSIRO, Australia in 1962. Polygodial is widely distributed, occurring in the roots, bark and leaves of several trees, in plants and...
Polygodial Pyridazine is a semi-synthetic derivative using the sesquiterpene dialdehyde, polygodial, as a scaffold. In contrast to polygodial, the pyridazine derivative is a poor inhibitor of Na+/K+-ATPase. Polygodial itself has antibiotic, antifungal,...
Penicinoline is an unusual quinolinone alkaloid isolated from a mangrove endophytic Penicillium species by researchers at the Key Laboratory of Marine Drugs in collaboration with Syngenta and first reported in 2010. Penicinoline posseses broadspectrum...
Pyrantel (+)-Tartrate is an anthelmintic (anti-protozoal) that was first described in 1965 (Pfizer). It is effective against intestinal nematodes (roundworm, threadworm, hookworm, and nodular worm). The product is soluble in DMSO. This product is...
Pyripyropene A is a meroterpenoid isolated from Aspergillus fumigatus and published in 1993 by Omura and co-workers at the Kitasato Institute, Japan. Pyripyropene A has potent acyl-CoA:cholesterol acyltransferase (ACAT) and the isozyme sterol...
Phenylpyropene A is a meroterpenoid isolated from Penicillium griseofulvum by researchers at the Korean Research Institute of Bioscience and Biotechnology in 2002. Phenylpyropene A inhibits conversion of cholesterol to cholesteryl esters via inhibition...
Radicinol is a mycotoxin isolated from Curvularia lunata (syn. Cochliobolus lunata) by researchers at Nagoya University, Japan in 1977. Subsequently, Radicinol has been found as a secondary metabolite in a diverse range of plant pathogenic fungi. ...
Roccellic Acid is a secondary metabolite and methyldodecylsuccinic acid isolated from lichen Roccella spp. over 150 years ago, with the structure fully elucidated by Akermark in 1962. Roccellic Acid is active against the oral bacteria, Streptococcus...
Salazinic Acid is a depsidone lichen metabolite first reported over a 100 years ago and widely distributed across many lichen genera. Salazinic Acid is moderately active against Gram-positive bacteria and some Gram-negative bacteria (P. aeruginosa and S...
Strychnospermine is an alkaloid isolated by Ritchie et al. at the University of Sydney, Australia from the Australian native strychnine tree, Strychnos psilosperma, in 1950. There are no published reports of the biological activity of Strychnospermine. ...
Seselin is a pyranocoumarin isolated from the fruits of Seseli indicum by Spath and colleagues in 1939. Seselin wassubsequently isolated from a number of fruits of diverse species, most notably star anise. More recently, Seselin has beenisolated...
