Antimicrobials

Pristinamycin

Pristinamycin is a streptogramin antibiotic. It is a mixture of Pristinamycin IA (a macrolide) and Pristinamycin IIA (streptogramin A), a depsipeptide). PI and PII are structurally unrelated but synergistic components. They are co-produced naturally in a...

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Virginiamycin B

Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by...

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Teicoplanin A2-2

Teicoplanin A2-2 is a major analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. They possess potent antibiotic activity against Gram-positive bacteria, including MRSA and Enterococcus faecalis. For more Teicoplanin...

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Tetromycin A

Tetromycin A is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin A has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria...

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Virginiamycin

Virginiamycin is a streptogramin, and a mixture of Virginiamycin M1 and Virginiamycin S1.  The commercial mixture is 75% Virginiamycin M1 and 25 % Virginiamycin S1, along with less abundant S analogs.  The two components of the mixture have...

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Viridicatumtoxin

Viridicatumtoxin is a tetracycline-like metabolite produced by several species of Penicillium, first isolated in 1976 as a mycotoxin. Initial testing revealed that viridicatumtoxin caused myocardial deterioration, renal tubule necrosis and spleen atrophy...

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Virginiamycin S1

Virginiamycin S1 is a cyclic hexadepsipeptide.  Together with Virginiamycin M1 as a mixture, it works synergistically against Gram-positive bacteria with bateriostatic properties.  Commercial preparations of Virginiamycin is 25% S1 and 75% M1...

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Tetromycin B

Tetromycin B is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin B has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria...

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Teicoplanin A2-3

Teicoplanin A2-3 is a major analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad-spectrum antibiotic activity against Gram-positive bacteria, including MRSA and E. faecalis.Teicoplanin A2-3...

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Thielavin A

The fungal metabolite, thielavin A, and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a inhibitor of prostaglandin biosynthesis. The closely related...

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Teicoplanin A2-4

Teicoplanin A2-4 is an analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram-positive bacteria, including MRSA and E. faecalis.Teicoplanin A2-4 is...

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Teicoplanin A2-5

Teicoplanin A2-5 is the most non-polar analog of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad-spectrum antibiotic activity against Gram-positive bacteria, including MRSA and E. faecalis...

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