Nigericin is a polyether antibiotic produced by Streptomyces, notably S. hygroscopicus, isolated in the 1950s. Its complex structure was finally elucidated in 1968. Although Nigericin can be isolated...
Narasin (4-methylsalinomycin) is a carboxylic polyether antibiotic isolated from Streptomyces aureofaciens in 1978. Although Narasin is a derivative of Salinomycin, the metabolites are produced by...
Narasin sodium is prepared from narasin taking advantage of the carboxylic acid which ionises and readily forms the salt in sodium hydroxide solutions. Narasin is an ionophore with broad spectrum...
Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidal antibiotic, also exhibiting antifungal and antiviral...
Delta-2-Avermectin B1a is a natural, irreversible base degradation product produced by selective hydrolysis of the terminal saccharide Avermectin under acidic conditions in animals and in the...
Enoxacin is a fluoroquinolone antibiotic with a broad spectrum (Gram-positive and Gram-Negative) of activity. Enoxacin was used to treat urinary tract infections and gonorrhea.Mechanism of...
Toxoflavin (PKF 118-310) is an azapteridine antibiotic produced by some species of Pseudomonas, Streptomyces, and Burkholderia gladioli that has antibiotic and anticancer properties. It is also a...
Cefotiam Dihydrochloride is a broad-spectrum, third-generation cephalosporin β-lactam antibiotic that was patented in 1973. It interferes with bacterial peptidoglycan synthesis. It is commonly used...
Fumagillin is a polyene natural product and mycotoxin isolated from Aspergillus fumigatus in 1951 as a potent antiprotozoan for agents that cause amoebiasis. More recently, Fumagillin has been shown...
Miconazole Nitrate is the nitrate salt of Miconazole, an imidazole antimycotic compound patented in 1968 (Janssen Pharmaceutica). It targets the fungi that cause tinea (ringworm) and athlete’s foot...
Chloramphenicol Succinate is prepared by acylation of chloramphenicol with succinic anhydride to provide a water soluble pro-drug. Chloramphenicol is released in the presence of succinate...
Pyrrole-2-carboxylic acid is small amphoteric polar metabolite produced by many Streptomyces species, often co-produced with its dimer, pyrocoll. Pyrrole-2-carboxylic acid is an important...
