Antimicrobials

Piperacillin

Piperacillin is a semi-synthetic, extended spectrum fungistatic β-lactam fourth-generation ureidopenicillin.  It was developed by Toyama Chemical Co, Tokyo, Japan and is derived from Ampicillin.  Piperacillin is commonly used in...

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Sulfapyridine, USP

Sulfapyridine, USP is a first generation sulfonamide discovered in 1937 by L Whitby (May & Baker) and originally named  M&B693.  Sulfapyridine has anti-inflammatory properties and can be used in studies of immunodeficiency and...

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Telithromycin

Telithromycin (Ketek, HMR 3647, RU 66647) is a semisynthetic antibacterial agent belonging to a class of compounds called ketolides, which are a variation on the existing class of antibiotics known as macrolides like erythromycin, whose structure...

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Sulfamonomethoxine

Sulfamonomethoxine is a bacteriostatic sulfonamide antibiotic which acts as a folic acid synthesis inhibitor.Mechanism of ActionLike most sulfonamides, sulfamonomethoxine inhibits folic acid synthesis by acting as a competitive inhibitor of...

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Tiamulin Fumarate

Tiamulin fumarate is a pleuromutilin antibiotic and is soluble in aqueous solution.Mechanism of ActionPleuromutilin antibiotics inhibit protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme...

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Clarithromycin, USP

Clarithromycin, USP is a macrolide antibiotic that is a derivative of Erythromycin.  This compound, developed in 1980, is both a substrate and inhibitor of CYP3A4.   Clarithromycin has anti-cancer properties.  Clarithromycin-related...

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Elaiophylin

Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase and is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and...

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Sulfamerazine Sodium

Sulfamerazine is a bacteriostatic sulfonamide antibiotic.  Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. It is a sulfonamide compound that inhibits bacterial synthesis of dihydrofolic acid by...

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Cetrimide

Cetrimide is a bactericidal cationic surfactant used against Gram-positive bacteria.  It is commonly used in selective media to isolate Pseudomonas aeruginosa. Cetrimide is an active ingredient in Cetavlon, a detergent used in plant surface...

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Ribostamycin Sulfate

Ribostamycin is an aminoglycoside antibiotic and is freely soluble in aqueous solution at 88.7 mg/mL. Ribostamycin is an aminoglycoside-aminocyclitol antibiotic isolated from Streptomyces ribosidificus, originally from a soil sample in Japan.  It is...

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Oxacillin Sodium, USP

Oxacillin Sodium, USP is the sodium salt of Oxacillin, semisynthetic penicillinase-resistant and acid-stable antibiotic of the penicillin class.  It is a narrow-spectrum β-lactam antibiotic primarily used against Gram-positive organisms. ...

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Sisomicin Sulfate

Sisomicin sulfate is a soluble broad-spectrum aminoglycoside antibiotic, and a dihydro analog of gentamicin C1a sulfate, Evopure.  Sisomicin was first isolated in 1970 from Micromonopora inyoensis, a novel strain at the time, that was...

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