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Oxozeaenol, (5E)-7-

(5E)-7-Oxozeaenol ("iso-LL Z1640-2") is a resorcylic acid lactone belonging to the Zearalenone class, recognised as a minor metabolite of the fungus, Drechslera portulacae. (5E)-7-Oxozeaenol was rediscovered as a major analog of a resorcylic acid lactone...

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Pluviatolide

Pluviatolide is a butyrolactone lignan first isolated from the Australian native plant, Zanthoxylum pluviatile, by Taylor and Ritchie in 1970. More recently, Pluviatolide and the related hinokinin were reported as metabolites of the vine, Aristolochia...

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Polygodial

Polygodial is a sesquiterpene dialdehyde first isolated from Persicaria hydropiper (syn. Polygonum hydropiper) by Loder atCSIRO, Australia in 1962. Polygodial is widely distributed, occurring in the roots, bark and leaves of several trees, in plants and...

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Polygodial Pyridazine

Polygodial Pyridazine is a semi-synthetic derivative using the sesquiterpene dialdehyde, polygodial, as a scaffold. In contrast to polygodial, the pyridazine derivative is a poor inhibitor of Na+/K+-ATPase. Polygodial itself has antibiotic, antifungal,...

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Penicinoline

Penicinoline is an unusual quinolinone alkaloid isolated from a mangrove endophytic Penicillium species by researchers at the Key Laboratory of Marine Drugs in collaboration with Syngenta and first reported in 2010. Penicinoline posseses broadspectrum...

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Pyrantel (+)-tartrate salt

Pyrantel (+)-tartrate salt is an anthelmintic (anti-protozoal) that was first desribed in 1965 by Pfizer. It is effective against intestinal nematodes (roundworm, threadworm, and hookworm, nodular worm). The compound is soluble in DMSO. This product is...

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Oritavancin

Oritavancin is a semi-synthetic glycopeptide antibiotic that is an analog of vancomycin. It has bactericidal activity against Gram-positive bacteria. Mechanism of Action Like other glycopeptides and lipoglycopeptides, Oritavancin inhibits...

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Pyripyropene A

Pyripyropene A is a meroterpenoid isolated from Aspergillus fumigatus and published in 1993 by Omura and co-workers at the Kitasato Institute, Japan. Pyripyropene A has potent acyl-CoA:cholesterol acyltransferase (ACAT) and the isozyme sterol...

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Phenylpyropene A

Phenylpyropene A is a meroterpenoid isolated from Penicillium griseofulvum by researchers at the Korean Research Institute of Bioscience and Biotechnology in 2002. Phenylpyropene A inhibits conversion of cholesterol to cholesteryl esters via inhibition...

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Radicinol

Radicinol is a mycotoxin isolated from Curvularia lunata (syn. Cochliobolus lunata) by researchers at Nagoya University, Japan in 1977. Subsequently, Radicinol has been found as a secondary metabolite in a diverse range of plant pathogenic fungi. ...

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Roccellic Acid

Roccellic Acid is a methyldodecylsuccinic acid isolated from Roccella spp. over 150 years ago, with the structure fullyelucidated by Akermark in 1962. Roccellic Acid is active against the oral bacteria, Streptococcus gordonii and Porphyromonas gingivalis...

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Salazinic Acid

Salazinic Acid is a depsidone lichen metabolite first reported over a 100 years ago and widely distributed across many lichen genera. Salazinic Acid is moderately active against Gram-positive bacteria and some Gram-negative bacteria (P. aeruginosa and S...

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